Clinics and Departments

Laboratory Services

Lab Dept:

Pathology

Test Name:

CHROMOSOME, BLOOD, BREAKAGE SYNDROME

General Information

Lab Order Codes:

BREAK

Synonyms:

Spontaneous Chromosomal Breakage

CPT Codes:

88230 – tissue culture for non-neoplastic disorders
88248 – Chromosome analysis for breakage syndromes; baseline breakage, score 50-100 cells, count 20 cells, 2 karotypes (eg, for ataxia telangiectasia, Fanconi anemia, fragile X).

Test Includes:

Determined by laboratory director based on clinical information.

Logistics

Test Indications:

Evaluation of baseline (sometimes referred to as spontaneous) chromosomal breakage may be indicated in patients who:

Have had intentional or accidental exposure to radiation or other clastogen exposure.

Are suspected of having a chromosomal instability disorder such as ataxia telangiectasia or Nijmegen Breakage Syndrome.

Lab Testing Sections:

Anatomic Pathology - Sendouts

Referred to:

Fairview University Cytogenetics

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

Results within 29 days.

Special Instructions:

Special tube required. See Container, contact the laboratory for appropriate tube.

Specimen

Specimen Type:

Whole blood

Container:

Green top (Sodium Heparin), no gel, tube

Draw Volume:

10 mL (Minimum: 5 mL) blood

Processed Volume:

Same as Draw Volume

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Do Not centrifuge. Forward specimen to Send Outs. Store and ship at room temperature. Must arrive at reference lab within 24 hours of collection.

Order in Atlas and include collect date/time, ordering MD, specimen type, diagnosis/reason for referral.

Patient Preparation:

None

Sample Rejection:

Improper storage, mislabeled or unlabeled specimen

Interpretive

Reference Range:

An interpretive report will be provided

Critical Values:

N/A

Limitations:

N/A

Methodology:

Methodology is determined by lab director based on clinical indications.

References:

Fairview University Laboratories September 2010



  Lab Test Directory
    Chemistry
    Coagulation
    Flow/Immunology
    Hematology
    Microbiology/ Virology
    Other Fluids
    Pathology
    Serology
    Transfusion Services
    Urine/Stool

  Search Lab Test Directory
    List All Documents

  Lab Staff

  E-mail Lab Services