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Lab Dept:
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Serology
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Test Name:
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ENDOMYSIAL IGA ANTIBODY
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General Information
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Lab Order Codes:
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ENDO
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Synonyms:
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Antiendomysial Aby; Antimesothelial Aby
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CPT Codes:
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86256 - Fluorescent noninfectious agent antibody; titer, each antibody
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Test Includes:
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Report includes presence and titer of circulating IgA endomysial antibodies.
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Logistics
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Test Indications:
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Useful for diagnosis of dermatitis herpetiformis and celiac disease. Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease. Because of the high specificity of Endomysial Antibodies for celiac disease, the test may obviate the need for multiple small bowel biopsies to verify the diagnosis. This may be particularly advantageous in the pediatric population, including the evaluation of children with failure to thrive.
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Lab Testing Sections:
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Serology - Sendouts
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Referred to:
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Mayo Medical Laboratories (Test# 9360)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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2 - 7 days; test set up Monday - Friday
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Special Instructions:
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See Mayo’s Celiac Disease algorithm for more information.
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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6.0 mL (Minimum: 1.5) blood
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Processed Volume:
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2.0 mL (Minimum: 0.5 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Centrifuge specimen, remove serum aliquot into screw-capped round bottom plastic vial. Store and ship refrigerated. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Report includes presence and titer of circulating IgA endomysial antibodies.
Negative in normal individuals; also negative in dermatitis herpetiformis or celiac disease patients adhering to a gluten-free diet.
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Critical Values:
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N/A
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Limitations:
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A negative result (absence of circulating IgA Endomysial Antibody) does not exclude the diagnosis of dermatitis herpetiformis or celiac disease.
Patients with mild gluten sensitive enteropathy may have a negative result.
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Methodology:
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Indirect Fluorescent Assay
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Contraindications:
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N/A
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References:
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Mayo Medical Laboratories Web Page November 2009
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Updates:
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4/14/2004: Test moved from Specialty Laboratories to Mayo Medical Laboratories.
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