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Lab Dept:
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Serology
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Test Name:
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HEPATITIS B CORE IgM ANTIBODY (ANTI-HBc IGM)
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General Information
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Lab Order Codes:
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HBCM
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Synonyms:
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Hepatitis B Core IgM Specific; Hepatitis Bc Antibody; Hepatitis B Core Antibody IgM Fraction
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CPT Codes:
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86705 – Hepatitis B core antibody; IgM antibody
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Test Includes:
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Hepatitis B Core IgM Specific Antibody reported as positive or negative.
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Logistics
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Test Indications:
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Diagnosis of acute hepatitis B infection. Identifying acute hepatitis B virus infection in the “core window” period, when HbsAg and anti-HBs are negative. Differentiation between acute and chronic hepatitis B infection when used in conjunction with anti-HBc IgG and IgM.
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Lab Testing Sections:
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Serology - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test# HBIM/9015)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 - 2 days; test setup daily
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Blood
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Container:
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Red top tube
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Draw Volume:
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3 mL (Minimum: 1.5 mL) blood
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Processed Volume:
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1 mL (Minimum: 0.5 mL) serum
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Collection:
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Routine venipuncture
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Special Processing:
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Lab Staff: Allow specimen to clot, centrifuge and remove serum within 24 hours of collection. Remove serum aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Gross hemolysis; warm specimens; gross lipemia; grossly icteric’ mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Negative
Note: A positive result indicates recent acute hepatitis B infection. A negative result suggests lack of recent exposure to the virus.
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Critical Values:
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N/A
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Limitations:
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Performance characteristics have not been established for the following specimen characteristics:
Grossly icteric: Total bilirubin level of >20 mg/dL
Grossly lipemic: Triolein level of >3000 mg/dL
Grossly hemolyzed: Hemoglobin level of >500 mg/dL
Containing particulate matter
Cadaveric specimens
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Methodology:
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Chemiluminescence Immunoassay
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References:
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Mayo Medical Laboratories Web Page September 2012
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Updates:
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4/6/2004: Test moved from Memoral Blood Center of Minneapolis to Mayo Medical Laboratories.
3/8/2005: Methodology previously listed as Enzyme Immunoassay.
9/27/2010: Specimen volume updates.
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