Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

HHV6 IgG/IgM ANTIBODIES

General Information

Lab Order Codes:

HHV6A

Synonyms:

Herpes Virus-6 Human IgG and IgM Antibodies

CPT Codes:

86790 x2 – Antibody; virus, not elsewhere specified

Test Includes:

HHV6 IgG and IgM Antibody titers.

Logistics

Test Indications:

Human herpesvirus 6 (HHV-6) infects peripheral blood leukocytes, and is considered the agent of roseola. The normal prevalence of HHV-6 antibody is high; nearly 100% of the population will demonstrate antibody at midlife with titers declining in old age. Immunofluorescence assays are used for serological detection of HHV-6. Crossreactions with other Herpes viruses, i.e., Cytomegalovirus and Herpes Simplex have not been found. In order to demonstrate primary infection, it is necessary to detect a significant change in titer.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Mayo Medical Laboratories forward to Focus Technologies, Inc. (MMLTest: 80419/FHP6) (Focus Test# 40540)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 - 4 days, test performed daily.

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3 mL (Minimum: 1.5 mL) blood

Processed Volume:

1 mL (Minimum: 0.5 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen. Remove serum aliquot into a plastic screw-capped vial. Store and ship specimen refrigerated. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than serum, mislabeled or unlabeled specimens

Interpretive

Reference Range:

HHV6 IgG:

<1:10

HHV6 IgM:

<1:20

Test performed by Focus Technologies, Inc., 5785 Corporate Ave., Cypress, CA 90630-4750.

Critical Values:

N/A

Limitations:

N/A

Methodology:

Indirect Fluorescence Antibody (IFA)

References:

Mayo Medical Laboratories June 2013

Focus Technologies, Inc. June 2013

Updates:

4/28/2004: Test moved from Specialty Laboratories to Mayo Medical Laboratories forward to Focus Technologies, Inc. Note: Test previously IgG only, now IgG/IgM.



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