Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

HISTOPLASMA ANTIGEN, URINE

General Information

Lab Order Codes:

UHIAG

Synonyms:

Histoplasma Ag, Urine; Histoplasma Polysaccharide Antigen

CPT Codes:

87385 - Infectious agent antigen detection by enzyme immunoassay technique. Qualitative or semiquantitatinve multiple step method; Histoplasma capsulatum
87385-59 – Confirmatory test (if appropriate)

Test Includes:

Histoplasma antigen result reported in ng/mL.

Logistics

Test Indications:

Aid for the diagnosis of Histoplasma capsulatum infection and to monitor quantitative Histoplasma antigen levels in urine. Patients having lived in or visited an endemic area may indicate possible exposure.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Mayo Medical Laboratories (Test: UHIST) and possible reflex forward to Mira Vista Diagnostics, Indianapolis, IN (Test: FMVHU)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1-2 days, test set up daily

Special Instructions:

N/A

Specimen

Specimen Type:

Urine, random
(Note: The sensitivity of antigen detection is greater using urine over serum.)

Container:

Urine Cup or other leakproof container

Draw Volume:

Submit entire random urine specimen

Processed Volume:

3 mL urine from a random urine collection (no preservative)

Collection:

Random or catheterized urine collection

Special Processing:

Lab Staff: Refrigerate specimen and send refrigerated to reference lab. Do Not use preservatives for collection.

Patient Preparation:

None

Sample Rejection:

Specimens other than urine; mislabeled or unlabeled specimens

Interpretive

Reference Range:

0.00 – 0.10

Negative

0.11 – 0.49

Indeterminate

>=0.50

Positive

Specimen with an Indeterminate result will be reflexed to Mira Vista Diagnostics for confirmation of result.

Confirmatory Reference Interval: None detected
Results are reported as ng/mL in 0.4 – 19 ng/mL

Results above the limit of detection but below 0.4 ng/mL are reported as “Positive, Below the Limit of Quantification”.

Results above 19 ng/mL are resported as “Positive, Above the Limit of Quantification”.

Critical Values:

N/A

Limitations:

N/A

Methodology:

Enzyme Immunoassay (EIA) for both base test and reflex.

References:

Mayo Medical Laboratories Web Page August 2014

Mira Vista Diagnostics Laboratories, Indianapolis, IN, 2014

Updates:

3/25/2004: Test moved from a direct referral to Mira Vista Diagnostics to a forward to the same laboratory through Mayo Medical Laboratories,
3/1/2007: Result changed units, previously reported at EIA Units. Note reference range changes.
4/1/2012: Reference range change.
8/14/2014: Test now performed at MML with reflex to Mira Vista if appropriate.



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