Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

COXSACKIE B ANTIBODY PANEL

General Information

Lab Order Codes:

COBA

Synonyms:

Myocarditis Antibodies

CPT Codes:

86658 x6 – Antibody; enterovirus

Test Includes:

Coxsackie B virus type 1 - 6 total antibodies

Logistics

Test Indications:

Useful for detecting total antibodies to coxsackie B virus types 1 – 6.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Mayo Medical Laboratories forward to Focus Technologies (Test: 80247/COXB)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 - 9 days, test performed Monday – Friday.

Special Instructions:

Designate whether specimen is acute or convalescent.

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

6 mL (Minimum: 1.5 mL) blood

Processed Volume:

2 mL (Minimum: 0.5 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, separate serum aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Improperly labeled specimen; gross hemolysis

Interpretive

Reference Range:

<1:8 Antibody not detected

≥1:8 Antibody detected

Single titers ≥1:32 are indicative of recent infection. Titers of 1:8 or 1:16 may be indicative of either past or recent infection, since Complement Fixation antibody levels persist for only a few months. A four-fold or greater increase in titer between acute and convalescent specimens confirms the diagnosis.

Test Performed by:
Focus Diagnostic
5785 Corporate Avenue
Cypress, CA 90630-4750

Critical Values:

N/A

Limitations:

There is considerable crossreactivity among enteroviruses; however, the highest titer is usually associated with the infecting serotype.

Methodology:

Complement Fixation (CF)

References:

Mayo Medical Laboratories June 2013

Focus Technologies Web Page (Focus Test 40335) June 2013

Updates:

3/2/2004: Test moved from Lab Corp (Viromed) to MML (forward to Focus Technologies). Test previously measured IgG antibody, now measures total antibody.



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