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Lab Dept:
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Serology
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Test Name:
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PARAINFLUENZA ANTIBODY
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General Information
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Lab Order Codes:
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PARI
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Synonyms:
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N/A
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CPT Codes:
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86790 x3 – Antibody, virus not elsewhere specified
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Test Includes:
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Parainfluenza virus types 1, 2, & 3 total antibody
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Logistics
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Test Indications:
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To support the diagnosis of parainfluenza infection.
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Lab Testing Sections:
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Serology - Sendouts
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Referred to:
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Mayo Medical Laboratories forward to Focus Technologies (Test# 80421)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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1 – 6 days, test set-up Sunday – Thursday.
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Whole blood
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Container:
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Red top tube
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Draw Volume:
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3 mL blood
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Processed Volume:
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1 mL (Minimum: 0.3 mL) serum
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Collection:
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Lab staff: Centrifuge specimen; remove serum aliquot in a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.
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Special Processing:
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Routine venipuncture
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Patient Preparation:
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None
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Sample Rejection:
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Excessive hemolysis, chylous serum, gross specimen contamination, specimen improperly labeled
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Interpretive
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Reference Range:
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<1:8 Antibody not detected
≥1:8 Antibody detected
Single titers of ≥1:64 are indicative of recent infection. Titers of 1:8 to 1:32 may be indicative of either past or recent infection, since complement fixation antibody levels persist for only a few months. A four-fold or greater increase in titer between acute and convalescent specimens confirms the diagnosis. After initial infection, antibody responses at a later date are often heterotypic and exhibit cross-reactivity with other paramyxoviruses (e.g. mumps).
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Critical Values:
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N/A
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Limitations:
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Heterotypic rises in parainfluenza titers may occur in infections with other viruses. Infant antibody response may be undetectable. Parainfluenza serology is not recommended for clinical diagnostic purposes.
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Methodology:
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Complement fixation (CF)
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Contraindications:
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N/A
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References:
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Mayo Medical Laboratories Web Page (October 2006)
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Focus Technologies Web Page www.focustechnologies.com
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Updates:
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3/18/2004: Test moved from Lab Corp (Viromed) to Mayo Medical Laboratories forward to Focus Technologies. Note: Test now measures total antibody.
10/6/2006: CPT code previously listed as 86171 x3.
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