Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

PARAINFLUENZA ANTIBODY

General Information

Lab Order Codes:

PARI

Synonyms:

Parainfluenza Virus Types 1, 2, 3

CPT Codes:

86790 x3 – Antibody, virus not elsewhere specified

Test Includes:

Parainfluenza virus types 1, 2, & 3 total antibody

Logistics

Test Indications:

To support the diagnosis of parainfluenza infection.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test: 80241/PARAV) forward to Focus Technologies (Test: 40755)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 – 9 days, test set-up Monday – Friday.

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3 mL (Minimum: 1.5 mL) blood

Processed Volume:

1 mL (Minimum: 0.5 mL) serum

Collection:

Lab staff: Centrifuge specimen; remove serum aliquot in a screw-capped round bottom plastic vial. Store and ship at ambient room temperature. Forward promptly.

Special Processing:

Routine venipuncture

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimen

Interpretive

Reference Range:

<1:8 Antibody not detected

≥1:8 Antibody detected

Single titers of ≥1:64 are indicative of recent infection. Titers of 1:8 to 1:32 may be indicative of either past or recent infection, since complement fixation antibody levels persist for only a few months. A four-fold or greater increase in titer between acute and convalescent specimens confirms the diagnosis. After initial infection, antibody responses at a later date are often heterotypic and exhibit cross-reactivity with other paramyxoviruses (e.g. mumps).

Critical Values:

N/A

Limitations:

Heterotypic rises in parainfluenza titers may occur in infections with other viruses. Infant antibody response may be undetectable. Parainfluenza serology is not recommended for clinical diagnostic purposes.

Methodology:

Complement fixation (CF)

References:

Mayo Medical Laboratories Web Page June 2013

Focus Technologies Web Page June 2013

Updates:

3/18/2004: Test moved from Lab Corp (Viromed) to Mayo Medical Laboratories forward to Focus Technologies. Note: Test now measures total antibody.

10/6/2006: CPT code previously listed as 86171 x3.



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