Clinics and Departments

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Lab Dept:

Serology

Test Name:

ICA 512 ANTIBODY

General Information

Lab Order Codes:

ICAAB

Synonyms:

ICA 512 Autoantibody; Islet Cell Cytoplasmic Autoantibodies

CPT Codes:

86341 - Islet cell antibody

Test Includes:

ICA 512 antibody reported in U/mL.

Logistics

Test Indications:

May be helpful in distinguishing between autoimmune type 1 diabetes and diabetes due to other causes.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Esoterix Laboratories (Test#: 500255)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

2 - 8 days; set up once a week on Wednesdays

Special Instructions:

Specimen must be processed in the laboratory within 1 hour of collection.

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

1.5 mL (Minimum: 0.3 mL) blood

Processed Volume:

0.5 mL (Minimum: 0.1 mL) serum

Note: Pediatric minimum is 0.1 mL, but does not allow for repeat analysis

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Within 1 hour of collection, centrifuge specimen and remove aliquot into a round bottom screw-capped plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Mislabeled or unlabeled specimens

Interpretive

Reference Range:

All ages:

<1.0 U/mL = Negative

>=1.0 U/mL = Positive

Critical Values:

N/A

Limitations:

Some patients who have type 1 diabetes will never develop detectible amounts of islet cell autoantibodies, although this is rare.

Methodology:

Immunoprecipitin Assay

References:

Esoterix Laboratories June 2013



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