|
|
Lab Dept:
|
Serology
|
Test Name:
|
LEUKOCYTE ADHESION DEFICIENCY TYPE 1
|
General Information
|
Lab Order Codes:
|
LAD1
|
Synonyms:
|
LAD (Leukocyte Adhesion Deficiency); CD11a; DA11b; CD18; LAD1
|
CPT Codes:
|
88184 – Flow cytometry; each cell surface, cytoplasmic or nuclear marker; first marker
88185 x2 - Flow cytometry; each cell surface, cytoplasmic or nuclear marker; each additional marker
|
Test Includes:
|
CD11a, CD11b and CD18 levels reported as Absent or Normal.
|
Logistics
|
Test Indications:
|
Aid in the diagnosis of LAD-1 syndrome, primarily in patients <18 years of age.
|
Lab Testing Sections:
|
Serology – Sendouts
|
Referred to:
|
Mayo Medical Laboratories (Test #: 81155)
|
Phone Numbers:
Minneapolis:
Saint Paul:
|
|
612-813-6280
|
651-220-6550
|
Test Availability:
|
Restricted Draw Times: To avoid specimen rejection due to limited specimen stability, collect sample Monday – Thursday morning.
|
Turnaround Time:
|
2 - 3 days, test set up Monday – Friday
|
Special Instructions:
|
Specimen must be processed at the reference laboratory within 24 hours of collection. Specimens 48 – 72 hours old will be processed and reported with a disclaimer if expression is absent.
|
Specimen
|
Specimen Type:
|
Whole blood
|
Container:
|
Lavender top (EDTA) tube
|
Draw Volume:
|
5.0 mL blood
|
Processed Volume:
|
Same as Draw Volume
|
Collection:
|
Routine venipuncture
|
Special Processing:
|
Lab Staff: Do Not centrifuge, maintain specimen at room temperature in original collection tube. Ship same day to arrive at Mayo within 24 hours of draw time. Do not send specimens after Thursday. Do Not refrigerate or freeze. Forward promptly.
|
Patient Preparation:
|
None
|
Sample Rejection:
|
Specimen older than 72 hours, mislabeled or unlabeled specimens
|
Interpretive
|
Reference Range:
|
Normal (reported as normal or absent expression of each marker)
|
Critical Values:
|
N/A
|
Limitations:
|
N/A
|
Methodology:
|
Flow Cytometric Immunophenotyping
|
References:
|
Mayo Medical Laboratories December 2009
|
