Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

PROTEINASE 3 ANTIBODIES, IGG, SERUM

General Information

Lab Order Codes:

P3AG

Synonyms:

Anticytoplasmic Autoantibodies; Antineutrophil Cytoplasmic Antibodies (ACPA); Cytoplasmic Neutrophil Antibodies; Perinuclear Antineurophil Cytoplasmic Antibodies (pANCA); Wegener’s Granulomatosis (WG)

CPT Codes:

83516 – Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; quantitative or semiquantitative, multiple step method

Test Includes:

Proteinase 3 Ab level reported in U.

Logistics

Test Indications:

Useful for evaluating patients suspected of having Wegener’s Granulomatosis (WG); distinguishing between WG and other forms of vasculitis, in conjunction with MPO/Myeloperoxidase antibodies, IgG, serum and ANCA cytoplasmic neutrophil antibodies, serum.

Lab Testing Sections:

Serology – Sendouts

Referred to:

Mayo Medical Laboratories (Test: PR3/82965)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

3 - 7 days

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

1.5 mL (Minimum: 1 mL) blood

Processed Volume:

0.5 mL (Minimum: 0.35 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove serum from cells, aliquot into a screw-capped round bottom plastic vial. Store and ship at refrigerated temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Gross hemolysis; gross lipemia; grossly icteric; mislabeled or unlabeled specimens

Interpretive

Reference Range:

Range:

Interpretation:

<0.4 U

Negative

0.4 – 0.9 U

Equivocal

>or = 1.0 U

Positive

Critical Values:

N/A

Limitations:

N/A

Methodology:

Multiplex Flow Immunoassay

References:

Mayo Medical Laboratories March 2013



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