Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

SCHISTOSOMA IGG ANTIBODY

General Information

Lab Order Codes:

SCHMA

Synonyms:

N/A

CPT Codes:

86682 – Antibody; helminth, not elsewhere specified

Test Includes:

Schistosoma IgG antibody level reported as detected or not detected.

Logistics

Test Indications:

Useful as an aid in the diagnosis of infections caused by Schistosoma mansomi (and other Schistosoma species on a limited basis).

Lab Testing Sections:

Serology – Sendouts

Referred to:

Mayo Medical Laboratories forward to Focus Diagnostics. (MML Test: FSCHS), (Focus Test: 40915)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

3 – 10 days

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3 mL (Minimum: 0.75 mL) blood

Processed Volume:

1 mL (Minimum: 0.25 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Centrifuge specimen, remove aliquot into a screw-capped, plastic vial. Store and ship at refrigerated temperatures.

Patient Preparation:

None

Sample Rejection:

Specimens other than serum; mislabeled or unlabeled specimens

Interpretive

Reference Range:

Interpretive criteria:

<1.00

Antibody not detected

> or = 1.00

Antibody detected

This assay utilizes the microsomal fraction of adult Schistosoma mansoni worms (MAMA) as antigen, and is thus highly specific (99%) and sensitive (96%) for detection of infection caused by S. mansoni. Although the assay is also highly specific for infections caused by other Schistosoma species (S. japonicum, S. haematobium, S. mekongi), its sensitivity for these infections is lower (55%). Antibody levels do not correlate with intensity of infection.

Critical Values:

N/A

Limitations:

Although the assay is also highly specific for infections caused by other Schistosoma species (S. japonicum, S. haematobium, S. mekongi), its sensitivity for these infections is lower (55%). Antibody levels do not correlate with intensity of infection.

Methodology:

Fluorescent Microsphere Immunoassay (FMI)

References:

Mayo Medical Laboratories October 2013
Focus Diagnostics
October 2013

   
   


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