|
|
|
Lab Dept:
|
Urine/Stool
|
Test Name:
|
AMINOLEVULINIC ACID, URINE RANDOM
|
General Information
|
Lab Order Codes:
|
UALAR
|
Synonyms:
|
Aminolevulinic Acid (ALA), Urine Random; Delta ALA, Urine Random; Delta Aminolevulinic Acid, Urine Random
|
CPT Codes:
|
82135 – Aminolevulinic acid, delta (ALA)
|
Test Includes:
|
Urine Aminolevulinic acid concentration reported in nmol/mL.
|
Logistics
|
Test Indications:
|
Useful for assistance in the differential diagnosis of the various porphyrias. As an Indicator of lead toxicity in children.
|
Lab Testing Sections:
|
Urine/Stool - Sendouts
|
Referred to:
|
Mayo Medical Laboratories (MML Test: ALAUR)
|
Phone Numbers:
|
MIN Lab: 612-813-6280
|
STP Lab: 651-220-6550
|
Test Availability:
|
Daily, 24 hours
|
Turnaround Time:
|
3 - 6 days, test set up Tuesday and Thursday at 8 am (not reported Saturday or Sunday)
|
Special Instructions:
|
N/A
|
Specimen
|
Specimen Type:
|
Urine, random
|
Container:
|
Plastic leakproof urine container
|
Draw Volume:
|
Entire Random urine collection
|
Processed Volume:
|
2 mL (Minimum: 1 mL) random urine
|
Collection:
|
Routine random urine collection
|
Special Processing:
|
Lab Staff: Remove urine aliquot. Store and ship the specimen at refrigerated temperatures. Forward promptly.
|
Patient Preparation:
|
Patient should abstain from alcohol for 24 hours prior to and during testing.
|
Sample Rejection:
|
Specimens other than urine; mislabeled or unlabeled specimens
|
Interpretive
|
Reference Range:
|
Age
|
Range (nmol/mL)
|
<1 year:
|
< or =10 nmol/mL
|
1 – 17 years:
|
< or =20 nmol/mL
|
> or = 18 years:
|
< or =15 nmol/mL
|
Critical Values:
|
N/A
|
Limitations:
|
The differential diagnosis of delta-aminolevulinic aciduria must be considered on the basis of the patient’s clinical presentation.
The preferred test for lead toxicity in children is blood lead.
|
Methodology:
|
Liquid chromatography – Tandem Mass Spectrometry (LC-MS/MS)
|
References:
|
Mayo Medical Laboratories Web Page August 2012
|