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Lab Dept:
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Urine/Stool
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Test Name:
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BLASTOMYCES ANTIGEN, URINE
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General Information
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Lab Order Codes:
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BAG
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Synonyms:
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N/A
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CPT Codes:
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87449 – Infectious agent antigen detection by EIA technique
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Test Includes:
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Urine Blastomyces Antigen level reported in EIA Units.
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Logistics
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Test Indications:
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Aid in diagnosis of disseminated or acute pulmonary blastomycosis.
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Lab Testing Sections:
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Urine/Stool - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test# 91407 forward to MiraVista Diagnostics)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours, test performed Monday - Friday
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Turnaround Time:
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1 - 3 days
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Urine, random
Other specimen types tested: Bronchoalveolar Lavage (BALF) or Sterile Body Fluid
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Container:
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Sterile leak-proof container
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Draw Volume:
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2.0 mL urine (or other acceptable specimen type)
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Processed Volume:
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Same as Draw Volume
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Collection:
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Routine urine collection
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Special Processing:
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Lab Staff: Mix random urine sample well. Remove aliquot into a plastic, 13 mL urine tube. Store and ship at refrigerated temperatures. Forward promptly.
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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EIA Units
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Result Interpretation
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Equivocal
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Results inconclusive after repeated testing
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<1.0
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Negative
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1.0 – 2.0
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Weak positive; suggest repeat
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2.1 – 4.0
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Positive; repeat if inconsistent with clinical findings
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4.1 – 10.0
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Moderate positive
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>10.0
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High positive
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Follow-up Testing Only (comparing to previous specimen tested in the same assay
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Increase:
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< or = 2.0
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Stable*
*No change: Increases or decreases <2.0 units are considered no change.
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2.1 – 4.0
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Mild increase; possible failure; probable failure
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>4.0
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Moderate to marked increase; probable failure
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Decrease:
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Current specimen having >2.0 unit decrease compared to result of prior specimen tested in the same assay is interpreted as having a decreased antigen level.
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Test performed by:
MiraVista Diagnostics
444 Decatur Blvd., Suite 300
Indianapolis, IN 46241
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Critical Values:
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N/A
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Limitations:
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Heterophile antibodies and rheumatoid factor can cause positive interference. Cross-reactions due to closely related antigenic epitopes are seen in patients with histoplasmosis, paracoccidioidomycosis, and penicilliosis. Rare cross-reactions have been seen in patients with aspergillosis and cryptococcosis.
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Methodology:
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EIA (Enzyme Immunoassay)
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Contraindications:
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N/A
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References:
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Mayo Medical Laboratories July 2009
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Updates:
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7/2/2009: Added other specimen types (BALF, other sterile body fluids)
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