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Lab Dept:
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Urine/Stool
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Test Name:
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OLIGOSACCHARIDE SCREEN, URINE
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General Information
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Lab Order Codes:
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OLGO
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Synonyms:
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N/A
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CPT Codes:
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84376 – Sugars (mono-, di-, oligosaccharides); single qualitative, each specimen
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Test Includes:
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This is a screening method, only a few oligosaccharidoses are detected. Sialidosis and Mucopolipidosis II and III are usually not detected. Confirm definite diagnoses by enzyme assay in serum, leukocytes, or fibroblasts.
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Logistics
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Test Indications:
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Investigation of possible oligosaccharidoses
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test: OLIGO/84340)
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Phone Numbers:
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MIN Lab: 612-813-6280
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STP Lab: 651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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4 – 8 days; performed Monday and Wednesday
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Special Instructions:
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Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
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Specimen
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Specimen Type:
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Urine, random collection
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Container:
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Plastic leakproof container (No preservatives)
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Draw Volume:
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3 mL (Minimum: 0.5 mL) urine
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Processed Volume:
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Same as Draw Volume
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Collection:
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A random urine sample may be obtained by voiding into a urine cup and is often performed at the laboratory. Bring the refrigerated container to the lab. Make sure all specimens submitted to the laboratory are properly labeled with the patient’s name, medical record number and date of birth.
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Special Processing:
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Lab Staff: Aliquot specimen into a 13 mL urine tube. Store and ship at frozen temperatures.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than urine; warm specimens; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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An interpretive report will be provided.
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Critical Values:
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N/A
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Limitations:
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The test can give false-negative results, especially in older patients with mild clinical manifestation. Patients with Sialidosis or Mucolipidosis II and III are usually not detected.
In neonates, many bands are often encountered and retesting between the ages of 6 months to 1 year is recommended.
Definite diagnoses should be confirmed by enzyme assay in serum, leukocytes, or fibroblasts.
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Methodology:
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Thin-Layer Chromatography (TLC)
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References:
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Mayo Medical Laboratories May 2013
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