Clinics and Departments

Laboratory Services

Lab Dept:

Urine/Stool

Test Name:

OLIGOSACCHARIDE SCREEN, URINE

General Information

Lab Order Codes:

OLGO

Synonyms:

N/A

CPT Codes:

84376 – Sugars (mono-, di-, oligosaccharides); single qualitative, each specimen

Test Includes:

This is a screening method, only a few oligosaccharidoses are detected. Sialidosis and Mucopolipidosis II and III are usually not detected. Confirm definite diagnoses by enzyme assay in serum, leukocytes, or fibroblasts.

Logistics

Test Indications:

Investigation of possible oligosaccharidoses

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test: OLIGO/84340)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 – 8 days; performed Monday and Wednesday

Special Instructions:

Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.

Specimen

Specimen Type:

Urine, random collection

Container:

Plastic leakproof container (No preservatives)

Draw Volume:

3 mL (Minimum: 0.5 mL) urine

Processed Volume:

Same as Draw Volume

Collection:

A random urine sample may be obtained by voiding into a urine cup and is often performed at the laboratory. Bring the refrigerated container to the lab. Make sure all specimens submitted to the laboratory are properly labeled with the patient’s name, medical record number and date of birth.

Special Processing:

Lab Staff: Aliquot specimen into a 13 mL urine tube. Store and ship at frozen temperatures.

Patient Preparation:

None

Sample Rejection:

Specimens other than urine; warm specimens; mislabeled or unlabeled specimens

Interpretive

Reference Range:

An interpretive report will be provided.

Critical Values:

N/A

Limitations:

The test can give false-negative results, especially in older patients with mild clinical manifestation. Patients with Sialidosis or Mucolipidosis II and III are usually not detected.

In neonates, many bands are often encountered and retesting between the ages of 6 months to 1 year is recommended.

Definite diagnoses should be confirmed by enzyme assay in serum, leukocytes, or fibroblasts.

Methodology:

Thin-Layer Chromatography (TLC)

References:

Mayo Medical Laboratories May 2013



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