Clinics and Departments

Laboratory Services

Lab Dept:

Urine/Stool

Test Name:

PURINE AND PYRIMIDINE PANEL, URINE

General Information

Lab Order Codes:

PPP

Synonyms:

5- hydroxylmethyluracil; Adenine, Adenosine; Deoxyadenosine; Deoxyguanosine; Deoxyinosine; Guanosine; Hyperuricemias; Hypoxanthine; Inosine; Orotic Acid; Pyrimidine; Succinyladenosine; Thymidine; Thymine; Uracil; Uric Acid; Uridine; Xanthine

CPT Codes:

83789 – Mass spectrometry and tandem mass spectrometry, quantitative, each specimen

Test Includes:

Random urine levels for Uracil, Uric Acid, Hypoxanthene and Xantine reported in mmol/mol creatinine.

Logistics

Test Indications:

Useful for evaluating treatment. Diagnosis and monitoring disorders of purine and pyrimidine metabolism; laboratory evaluation of primary and secondary hyperuricemias.

Lab Testing Sections:

Chemistry - Sendouts

Referred to:

Mayo Medical Laboratories (MML Test #: 81420)

Phone Numbers:

Minneapolis:

Saint Paul:

 

612-813-6280

651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

4 - 10 days, set up once weekly

Special Instructions:

N/A

Specimen

Specimen Type:

Urine, random

Container:

Screw-capped urine container

Draw Volume:

Entire random collection

Processed Volume:

3 mL (1 mL) random urine aliquot

Collection:

Voided or catheterized urine specimen

Special Processing:

Lab Staff: Mix specimen well, remove urine aliquot into a screw-capped plastic 13 mL urine tube. Store and ship at frozen temperatures.

Patient Preparation:

None

Sample Rejection:

Specimens other than urine; warm specimens; mislabeled or unlabeled specimens

Interpretive

Reference Range:

Uracil (mmol/mol creatinine)

0 – 2 years

< or =31

3 – 5 years

< or =30

6 – 11 years

< or =28

12 – 17 years

< or =26

> or =18 years

< or =35

Uric Acid (mmol/mol creatinine)

0 – 2 years

< or =2249

3 – 5 years

< or =1900

6 – 11 years

< or =1398

12 – 17 years

< or =698

> or =18 years

< or =669

Hypoxanthine (mmol/mol creatinine)

0 – 2 years

<53

3 – 5 years

<49

6 – 11 years

<43

12 – 17 years

<36

> or =18 years

<40

Xanthine (mmol/mol creatinine)

0 – 2 years

<49

3 – 5 years

<41

6 – 11 years

<30

12 – 17 years

<16

> or =18 years

<51

Critical Values:

N/A

Limitations:

No significant cautionary statements

Methodology:

Liquid chromatography-tandem mass spectrometry (LC-MS/MS)

References:

Mayo Medical Laboratories February 2011

Updates:

12/23/2010: Units update, no change in reference ranges
2/28/2011: Reference range updates.



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