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Lab Dept:
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Urine/Stool
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Test Name:
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PURINE AND PYRIMIDINE PANEL, URINE
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General Information
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Lab Order Codes:
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PPP
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Synonyms:
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5- hydroxylmethyluracil; Adenine, Adenosine; Deoxyadenosine; Deoxyguanosine; Deoxyinosine; Guanosine; Hyperuricemias; Hypoxanthine; Inosine; Orotic Acid; Pyrimidine; Succinyladenosine; Thymidine; Thymine; Uracil; Uric Acid; Uridine; Xanthine
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CPT Codes:
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83789 – Mass spectrometry and tandem mass spectrometry, quantitative, each specimen
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Test Includes:
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Random urine levels for Uracil, Uric Acid, Hypoxanthene and Xantine reported in mmol/mol creatinine.
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Logistics
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Test Indications:
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Useful for evaluating treatment. Diagnosis and monitoring disorders of purine and pyrimidine metabolism; laboratory evaluation of primary and secondary hyperuricemias.
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Lab Testing Sections:
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Chemistry - Sendouts
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Referred to:
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Mayo Medical Laboratories (MML Test #: 81420)
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Phone Numbers:
Minneapolis:
Saint Paul:
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612-813-6280
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651-220-6550
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Test Availability:
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Daily, 24 hours
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Turnaround Time:
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4 - 10 days, set up once weekly
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Special Instructions:
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N/A
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Specimen
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Specimen Type:
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Urine, random
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Container:
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Screw-capped urine container
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Draw Volume:
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Entire random collection
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Processed Volume:
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3 mL (1 mL) random urine aliquot
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Collection:
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Voided or catheterized urine specimen
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Special Processing:
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Lab Staff: Mix specimen well, remove urine aliquot into a screw-capped plastic 13 mL urine tube. Store and ship at frozen temperatures.
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Patient Preparation:
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None
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Sample Rejection:
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Specimens other than urine; warm specimens; mislabeled or unlabeled specimens
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Interpretive
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Reference Range:
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Uracil (mmol/mol creatinine)
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0 – 2 years
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< or =31
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3 – 5 years
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< or =30
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6 – 11 years
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< or =28
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12 – 17 years
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< or =26
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> or =18 years
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< or =35
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Uric Acid (mmol/mol creatinine)
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0 – 2 years
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< or =2249
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3 – 5 years
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< or =1900
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6 – 11 years
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< or =1398
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12 – 17 years
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< or =698
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> or =18 years
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< or =669
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Hypoxanthine (mmol/mol creatinine)
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0 – 2 years
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<53
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3 – 5 years
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<49
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6 – 11 years
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<43
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12 – 17 years
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<36
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> or =18 years
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<40
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Xanthine (mmol/mol creatinine)
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0 – 2 years
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<49
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3 – 5 years
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<41
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6 – 11 years
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<30
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12 – 17 years
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<16
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> or =18 years
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<51
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Critical Values:
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N/A
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Limitations:
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No significant cautionary statements
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Methodology:
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Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
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References:
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Mayo Medical Laboratories February 2011
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Updates:
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12/23/2010: Units update, no change in reference ranges
2/28/2011: Reference range updates.
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