Clinics and Departments

Laboratory Services

Lab Dept:

Urine/Stool

Test Name:

CALPROTECTIN, STOOL

General Information

Lab Order Codes:

CALPS

Synonyms:

N/A

CPT Codes:

83993 – Calprotectin, fecal

Test Includes:

Stool Calprotectin level reported in mcg/g.

Logistics

Test Indications:

Fecal calprotectin can be used to differentiate between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD); to monitor treatment in IBD, and to determine which patients should be referred for endoscopy and/or colonoscopy.

Lab Testing Sections:

Urine/Stool – Sendouts

Referred to:

Mayo Medical Laboratories forward to Genova Diagnostics (MML Test: FCALP)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

7 – 11 days

Special Instructions:

N/A

Specimen

Specimen Type:

Random stool

Container:

Screw-capped, plastic container

Draw Volume:

10 grams stool

Processed Volume:

Same as Draw Volume

Collection:

Routine random stool collection, no preservative

Special Processing:

Lab Staff: Stool should be in a plastic screw-capped container. Collection date and time is required. Freeze specimen. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than stool; mislabeled or unlabeled specimens

Interpretive

Reference Range:

< or =50 mcg/g

Interpretation: Calprotectin is a neutrophilic marker specific for inflammation in the gastrointestinal tract. It is elevated with infection, post-infectious IBS, and NSAID enteropathy. Fecal calprotectin can be used to differentiate IBD vs IDS, and to determine which patients should be referred for endoscopy and/or colonoscopy. Levels between 50 – 120 mcg/g should be repeated in 4-6 weeks and confirmed.

Critical Values:

N/A

Limitations:

Commentary is provided to the practitioner for educational purposes, and should not be interpreted as diagnostic or treatment recommendations. Diagnosis and treatment decisions are the responsibility of the practitioner.

Methodology:

Enzyme Linked Immunosorbent Assay (ELISA)

References:

Mayo Medical Laboratories October 2013
Genova Diagnostics
October 2013

   
   


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