Clinics and Departments

Laboratory Services

Lab Dept:

Serology

Test Name:

HEPATITIS A IgM ANTIBODY (ANTI-HAV IgM)

General Information

Lab Order Codes:

HAVM

Synonyms:

Hepatitis A Virus IgM Antibody

CPT Codes:

86709 – Hepatitis A antibody, IgM

Test Includes:

Hepatitis A IgM Antibody reported positive or negative.

Logistics

Test Indications:

Useful for diagnosis of a recent acute or subclinical hepatitis A infection. In most cases, antibody against hepatitis A antigen is detectable at the onset of symptoms (usually 15-45 days after exposure). Initial antibody consists almost entirely of the IgM subclass. Anti-HAV, IgM usually falls to undetectable levels 3-6 months after hepatitis A infection. Anti-HAV, IgG levels rise quickly once the virus is cleared and may persist for many years.

Lab Testing Sections:

Serology - Sendouts

Referred to:

Mayo Medical Laboratories (Test# 8342)

Phone Numbers:

Minneapolis:

Saint Paul:

 

612-813-6280

651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 – 2 days, test performed daily.

Special Instructions:

N/A

Specimen

Specimen Type:

Blood

Container:

Red top tube

Draw Volume:

3.0 mL (Minimum: 1.5 mL) blood

Processed Volume:

1.0 mL (Minimum: 0.5 mL) serum

Collection:

Routine venipuncture

Special Processing:

Lab Staff: Allow specimen to clot, centrifuge within 24 hours of collection, remove serum/plasma aliquot into a screw-capped round bottom plastic vial. Store and ship at frozen temperatures. Forward promptly.

Patient Preparation:

None

Sample Rejection:

Specimens other than serum, gross hemolysis, multiple freeze thaw cycles, gross lipemia, mislabeled or unlabeled specimens

Interpretive

Reference Range:

Negative

Critical Values:

N/A

Limitations:

Positive anti-HAV IgM test results should be reported by the attending physician to the State Department of Health, as required by law in some states. Consider administration of immune globulin to contacts. Not useful for detection of acute hepatitis A following exposure and prior onset of symptoms.

Not useful for detection of acute hepatitis A following exposure and prior onset of symptoms.

Methodology:

Enzyme Immunoassay (EIA)

Contraindications:

N/A

References:

Mayo Medical Laboratories Web Page April 2007

Updates:

4/6/2004: Test moved from Memorial Blood Center of Minneapolis to Mayo Medical Laboratories.



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