In 2011, the St. Baldricks's Foundation, a charity dedicated to raising money for childhood cancer research, awarded Kris Ann P. Schultz, MD, a pediatric oncologist in the cancer and blood disorders program at Children's Hospitals and Clinics of Minnesota, a $330,000 grant to establish the International Ovarian and Testicular Stromal Tumor (OTST) Registry.

The OTST Registry is the nation's first registry to study rare ovarian and testicular tumors that occur in children and adolescents. The registry hopes to collect tumor and blood samples to determine what causes ovarian and testicular stromal tumors, who is at risk and what therapies work best for treatment – with the ultimate goal of increasing survival rates and reducing late effects.

The registry collects cases of ovarian and testicular sex cord-stromal tumors.

Examples of ovarian tumors eligible for the registry include:

  • Sertoli Leydig cell tumors
  • Juvenile granulosa cell tumors
  • Gynandroblastomas
  • Sex cord-stromal tumor with annular tubules
  • Undifferentiated sex cord-stromal tumors

Examples of testicular tumors eligible for the registry include:

  • Juvenile granulosa cell tumors
  • Leydig cell tumors
  • Sertoli tumors
  • Sex cord-stromal tumor with annular tubules
  • Undifferentiated sex cord-stromal tumors

In addition, the registry can help facilitate central pathology review and DICER1 testing. By collecting cases and studying these rare tumors, investigators hope to find ways to treat ovarian and testicular stromal tumors as well as other more common cancers.

For more information about the OTST Registry, call or email the registry coordinator, Anne Harris: 612-813-5861, This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

The International OTST Registry is a collaboration of Children's Hospitals and Clinics of Minnesota, Children's National Medical Center and Dana Farber Cancer Institute.

The International Ovarian and Testicular Stromal Tumor Registry is funded by St. Baldrick's Foundation, Hyundai Hope on Wheels and the Pine Tree Apple Tennis Classic, a local charity dedicated to children's cancer research.