Children's Hospitals and Clinics of Minnesota
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CRITICAL LIMITS FOR LABORATORY TEST VALUES

*Critical values will be reported only for tests that are ordered. No results for unordered tests will be given.

*Critical values are posted in the on-line laboratory handbook.

*Laboratory personnel will initiate notification of an appropriate caregiver (physician, house staff, or nurse) of any defined critical value(s) detected within 20 minutes of detection of the result in the lab. After 20 minutes, the Organizational Policy #201, “Chain of Command of the Unstable Patient”, will be followed.

*Multiple, repetitive critical results will be notified each new calendar day.

*Reference separate Microbiology/Virology/Molecular/Histology and Pathology critical policy procedures.

DEPARTMENT/TEST

VALUE

HEM/ONC CLINICS

CRITICAL TESTS (The following two tests will be called every time regardless of result)

Frozen Section of Surgical Specimens: 90% within CAP Guidelines of 20 minutes.

Gram Stains

All CSF gram stains (positive or negative)

All CSF gram stains (positive or negative)

CRITICAL RESULTS (The following test results will be called based on defined result ranges and policies listed above)

CHEMISTRY

Ammonia

>150 umol/L

None

Bilirubin, Total

>12 mg/dL at <one day old

>15 mg/dL all others

None

Calcium

<3 - >7 mEq/L

None

Carbon Dioxide

<10 - >40 mEq/L

<10 - >40 mEq/L

CPK

>4000 U/L

None

HCO3

<10 - >40 mEq/L

None

Glucose

<50 - >300 mg/dL

None

Ionized Calcium

<1.5 mEq/L

None

Lactate

>45 mg/dL

None

Lead

>30 ug/dL

>30 ug/dL

Magnesium

<1 - >5.5 mEq/L

None

pCO2

<15 - >70 mm Hg

None

pH

<7.2 - >7.6

None

Phosphorus

<2 - >10 mg/dL

None

pO2 (Arterial)

<40 mm Hg

None

Potassium

<2.5 - >6.5 mEq/L

<2.5 - >6.5 mEq/L

Sodium

<124 - >156 mEq/L

<124 - >156 mEq/L

Uric Acid

>10 mg/dL

None

COAGULATION

Fibrinogen

<80 mg/dL

None

Protime

>17 seconds

None

WPT (INR) Patients on warfarin therapy

<1.4

>3.5

PTT

>48 seconds

None

Thrombin Time

>25 seconds

None

HEMATOLOGY

Hemoglobin

<7.0 gm/dL

<5.0 gm/dL

Hematocrit

<21 - >65%

None

Platelets

<50,000 - >1,000,000

<5,000

WBCs

Newborn <5,000 - >35,000

Others <2,000 - >25,000

None

Morphology

Presence of blasts

Presence of blasts

CEREBROSPINAL FLUID

Protein

>150 mg/dL

None

Glucose

<31 mg/dL

None

MICROBIOLOGY/VIROLOGY

AFB-TB

Positive

Positive

Blood Culture

Positive

Positive

Body Fluid (sterile) Culture

Positive

Positive

CSF Culture

Positive

Positive

Fungal Culture – Syst Infect

Positive

Positive

MRSA Screen/Culture

Positive

Positive

MRSA PCR

Positive

Positive

Viral Culture – Syst Infect

Positive

Positive

TOXICOLOGY

Acetaminophen

>25 ug/mL

>25 ug/mL

Carbamazepine

>20 ug/mL

>20 ug/mL

Gentamicin

>10 ug/mL

>10 ug/mL

Methotrexate

>1 umol/mL

>1 umol/mL

Phenobarbital

>60 ug/mL

>60 ug/mL

Phenytoin

>30 ug/mL

>30 ug/mL

Salicylate

>30 mg/dL

>30 mg/dL

Theophylline

>25 ug/mL

>25 ug/mL

Tobramycin

>10 ug/mL

>10 ug/mL

Valproic Acid

>200 ug/mL

>200 ug/mL

Vancomycin

>50 ug/mL

>50 ug/mL

Urine Toxicology Screen

Any positive

Any positive

BLOOD BANK

Any undue delay in transfusing a patient due to the inability to find a compatible product or due to the unavailability of a product.

Acute hemolytic or anaphylactic reaction.

Identification of a blood product as potentially contaminated by bacteria after the unit has been transfused.

REFERENCE LAB

Any critical limit phoned as defined by the reference laboratory.

Updated: 6/21/2009