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Children’s publishes 2009 Research Report

Children’s has published the 2009 Research Report, which showcases a representation of the research being conducted at Children’s.

The researchers at Children’s are recognized internationally for their excellent care and outcomes. Our professional staff has been invited to participate in networks, consult as experts, and coordinate cooperative agreements in national initiatives and clinical research trial networks. Partnerships with entities such as the Therapeutic Development Network of the Cystic Fibrosis Foundation, Children’s Oncology Group, and the Pediatric Heart Network enable clinical research centers worldwide to consolidate research efforts and provide patients with leading edge treatments.


Research areas highlighted in this report include:

Diabetes/endocrinology- read summary

Cystic fibrosis- read summary

Cardiovascular and critical care- read summary

Hematology/oncology – read summary

The Telehealth Institute for Child Maltreatment (THICM)read summary

The Infant Diagnostic and Research Center (IDRC)read summary

View full 2009 Research Report


  • Children’s McNeely Diabetes Center and Endocrine Clinic is currently involved in nine open clinical studies.
  • As part of a multi-center trial, Children’s is partnering with Medtronic to investigate the use of newer diabetes technology for children.

View full Research Report

Cystic fibrosis

  • In 2009, the CF program at Children’s was awarded Therapeutic Development Network (TDN) Center status through the CF Foundation, which is providing Children’s with the potential to pursue new networking and research opportunities.
  • The Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS) is exploring the use of 7 percent hypertonic saline in patients with CF
  • Children’s is also collaborating with Inspire Pharmaceuticals, Inc. on a multi-center, randomized trial to evaluate the use of denufosol (an investigational drug) vs. placebo delivered via inhalation.

View full Research Report

Cardiovascular and critical care (CVCC)

  • A Children’s physician initiated the collaboration of five pediatric institutions in a retrospective analysis of the treatment of patients with unbalanced atrioventricular septal defect (AVSD).
  • Children’s physicians are exploring the effects of atenolol and losartan on aortic root growth, a leading cause of death in individuals with marfan syndrome. The clinical trial with 30 sites throughout the U.S., Canada, and Europe, is sponsored by the National Heart, Lung, and Blood Institute and conducted through the Pediatric Heart Network.
  • An institution-wide study is being conducted to improve the care of children with pneumonia and empyema (chest cavity infection) by creating a clinical benchmark that minimizes practice variation and limits delay in decision-making.

View full Research Report


  • National recognition for identifying the DICER1gene and continues leading-edge investigator-initiated research to help children with cancer live developmentally normal lives.
  • With 132 clinical research-driven specialty studies, 95 of which are clinical trials, Children’s is at the forefront of pediatric oncology research with ongoing studies that are well-integrated into national research.
  • Children’s Hemophilia Treatment Center (HTC) belongs to a nationwide network of federally funded hemophilia and thrombosis centers and is the only such program in the region focused solely on pediatrics.”

View full Research Report

The Telehealth Institute for Child Maltreatment (THICM)

  • THICM reaches across the nation to ensure that any child who is a victim o sexual abuse receives and appropriate and timely diagnosis.
  • Research is being conducted on the collated pre and post review data to determine and analyze case demographics, trends, and the effectiveness of THICM in the accurate diagnosis of child abuse.

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The Infant Diagnostic and Research Center (IDRC)

  • Researchers within the Infant Diagnostic and Research Center, founded in 1979, have produced more than 100 publications and actively participate in local and national research projects.
  • In a multi-center, randomized controlled trial, Children’s researchers explored the efficacy of enteral feedings during the time an infant is being treated with indomethacin or ibuprofen.

View full Research Report