When to Collect a Specimen
Collect sample before discharge from hospital of birth, as mandated by statute. If initial sample was collected before 24 hours of age, obtain repeat sample in about 14 days, as recommended by the American Academy of Pediatrics. (Pediatrics, Vol. 89 No. 2, Feb. 1992)
The Newborn Screening Statute applies to all births in Wisconsin. The birth attendant (physician, midwife, or nurse certified under 441.15) is responsible for collecting a sample before one week of life for out-of-hospital births.
Extended Hospital Stays (Low Birth weight/Sick Infants):
Collect specimen by the seventh day of life unless a transfusion is imminent (see below). For birth weight below 2,200g collect 2nd specimen around 2 weeks of age, a 3rd around 30 days and monthly thereafter until discharge. Should any of the collections occur post-transfusion, follow re-testing guidelines on the laboratory report. For babies weighing more than 2,200g and hospital stays greater than 14 days re-test at time of discharge or at one month of age if hospital stay is longer than one month.
NOTE: Always collect a newborn screening specimen (filter paper) at discharge unless the previous specimen was collected within 6 days of discharge.
Collect initial sample before transfusion, if possible.
● If sample is collected before transfusion and less than 24 hours of age, repeat testing at 30 and 60 days of life.
● If initial sample was collected post-transfusion, testing should be done at 6, 30, and 60 days of life. Always list date of most recent transfusion on sample collection card.
If transfer to another hospital is imminent, collect sample before transfer, if at all possible. Be sure to inform the receiving hospital of collection status, including whether or not the sample was collected, age at time of collection, transfusion status, etc.
Parent Refusal of Newborn Screening Testing:
Parents may refuse newborn screening testing of their baby ONLY "on the grounds that it conflicts with their religious tenets and practices". Parents refusing under this condition should sign a statement that is placed in the infant's medical record.