Clinics and Departments

Laboratory Services

Lab Dept:


Test Name:


General Information

Lab Order Codes:

DDUM (Back-up only)


Fibrin D-Dimer; D-Dimer Quantitative

CPT Codes:

85379 – Fibrin degradation products, D-dimer; quantitative

Test Includes:

Fibrin D-Dimer reported in ugFEU/mL.


Test Indications:

D-Dimer is a specific marker of the breakdown of a cross-linked fibrin clot and an indirect marker of clot formation. Elevated levels of D-Dimer are present in a wide variety of disorders known to be associated with activation of coagulation including pre-DIC/DIC conditions; sickle cell disease; pregnancy; renal diseases; arterial thrombosis; venous thromboembolism.

Lab Testing Section:

Coagulation - Sendouts

Referred to:

Fairview University Medical Center (Fairviw/Atlas: DD)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

Results reported within 7 days, test performed once a week

Special Instructions:



Specimen Type:

Whole blood


Light Blue top tube (Buffered Na Citrate 3.2%)

Draw Volume:

2.7 mL (Minimum volume: 1.8 mL in 2 mL tube) blood

Processed Volume:

Specimen will be processed by the reference lab facility.


Do Not use the first 2 mL’s of blood collected. For correct anticoagulant to blood ratio, place 2.7 mL’s of blood in a 3 mL tube or 4.5 mL’s of blood in 5 mL tube. If the patient’s hematocrit is >55%, contact laboratory to obtain a special tube. Mix thoroughly by gentle inversion.

Special Processing:

Lab Staff: Do Not process. If more than 24 hours is required for transport, contact laboratory for processing instructions. Ship at room temperature.

Patient Preparation:


Sample Rejection:

Improper tube; clotted specimens; underfilled tubes; overfilled tubes; mislabeled or unlabeled specimens


Reference Range:

0.0 – 0.50 ugFEU/mL correlates to a negative qualitative test.

A quantitative D-dimer of 0.6 – 3.0 ugFEU/mL correlates to an FDP of 10 – 30 ug/mL.

Critical Values:



Elevated D-dimer levels are not specific for the presence of DIC or of deep vein thrombosis. False-positive or false-negative results may occur when attempting to confirm a diagnosis of DIC.




Fairview University Laboratory Web Page September 2013


5/24/2010: Tubing patient specimens is no longer prohibited.

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