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Granisetron (Kytril)

How does this medicine work?

Granisetron (gra-NI-se-tron) is a medicine used to treat and prevent nausea and vomiting.

How is the medicine given?

Granisetron may be given by mouth as a liquid or tablet or in a vein through an IV. This medication may be given as needed or at regular times throughout the day.

Are there any precautions about food or other medications?

This medicine may be given with or without food. Check with you or your child’s provider before giving any other prescription or non-prescription medications, herbs, or vitamins.

What are the side effects?


  • Headache
  • Constipation


  • Fatigue
  • Diarrhea
  • Feeling dizzy
  • Change in liver tests (with long term use)
  • Heart rhythm changes

When should I call the clinic?

Call the clinic if:

  • Continued vomiting after 2 doses
  • Bleeding, unusual bruising
  • Fevers, chills
  • Cough, shortness of breath, sore throat
  • Signs of an allergic reaction:

            - rash or hives

            - wheezing

            - trouble breathing-call 911

What else do I need to know?

You and your child should know the names of all the medicines he or she is taking. Share this information with anyone involved in your child’s care.

Always make sure you have enough medication on hand. Each time you refill your prescriptions, check to see how many refills are left. If no refills are left, the pharmacist will need 2 or 3 days to contact the provider to renew the prescription.

Store all medicines in their original container and away from direct sunlight or heat. Do not store in humid places such as the bathroom. Keep them out of children’s reach, locked up if possible.

If too much OR the wrong medicine is taken, call the oncology clinic right away. If your child is unconscious or has a seizure, call 911


This sheet is not specific to your child but provides general information. If you have any questions, please call the oncology clinic or pharmacy.

Reviewed by Hem/Onc 12/2016

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This page is not specific to your child, but provides general information on the topic above. If you have any questions, please call your clinic. For more reading material about this and other health topics, please call or visit Children's Minnesota Family Resource Center library, or visit

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