Lab Dept:

Anatomic Pathology

Test Name:


General Information

Lab Order Codes:

Orders are communicated via the Surgical Pathology request form


Renal Biopsy; Open Kidney Biopsy; Needle Biopsy of Kidney

CPT Codes:

88305 – Level IV, surgical pathology gross and microscopic examination (if appropriate)
88313 – Special stains, each (if appropriate)
88347 x4 – Immunofluorescent study, each antibody; indirect method (if appropriate)
88348 – Electron microscopy (if appropriate)

Test Includes:

Light microscopy. May also include a battery of histochemical stains and EM if pathologist deems necessary.


Test Indications:

Useful for evaluation of acute and/or chronic renal disease

Lab Testing Sections:

Anatomic Pathology

Referred to:

Referrals will be designated by the pathologists handling the case.

Electon Microscopy (EM): Hennepin County Medical Center

Phone Numbers:

MIN Lab: 612-813-5875

STP Lab: 651-220-6561

Test Availability:

Monday – Friday

Turnaround Time:

1 - 7 days

Special Instructions:

Specimen must arrive within 4 hours of collection. Call Histology department 24 hours prior to collection for complete instructions, supplies, and to notify them for preparation of receipt of kidney biopsy.


Specimen Type:



Saline moistened gauze or B5/Glutarahldhyde fixatives

Draw Volume:

Entire specimen collected (to include three separate pieces of kidney)

Processed Volume:

Same as Draw Volume


Submit sterile, fresh kidney tissue with no added fixative. Place specimen in a saline moistened gauze. Never allow specimen to dry out. Maintain sterility and forward promptly at ambient temperature only. The nephrologist may pick up fixatives (B-5 or glutaraldehyde) and place specimen in appropriate fixatives. The nephrologist will prepare specimen for immunofluorescence (IF).

EM: Place kidney tissue in EM fixative (glutaraldehyde).


Special Processing:

See Collection

Patient Preparation:

Physician preference

Sample Rejection:

Improperly collected specimen; unlabeled or mislabeled specimen


Reference Range:

Interpretive pathology report


Electron Microscopy


Rosai, Juan MD, Ackerman’s Surgical Pathology, 8th ed, vols 1 and 2, CV Mosby

Sternberg, Steven (1997) Histology for Pathologists, 2nd ed, Lippincott/Raven

Hennepin County Medical Center Laboratory, 2005


11/15/2005: Previously sent to Veteran’s Administration Medical Center Laboratory