Lab Dept:


Test Name:


General Information

Lab Order Codes:



Clauss Fibrinogen; Plasma Fibrinogen; Fibrinogen Activity

CPT Codes:

85384 – Fibrinogen; activity

Test Includes:

Fibrinogen Activity reported in mg/dL.


Test Indications:

Used for identifying congenital afibrinogenemia, dysfibrinogenemia, disseminated intravascular coagulation (DIC), fibrinolytic activity and severe liver disease.

Lab Testing Section:

Coagulation - Sendouts

Referred to:

Fairview University Medical Center (Test: FIBR)

Phone Numbers:

MIN Lab: 612-813-6280

STP Lab: 651-220-6550

Test Availability:

Daily, 24 hours

Turnaround Time:

1 day

Special Instructions:

Deliver immediately to the laboratory; indicate when specimen is drawn from a line or a heparin lock.


Specimen Type:

Whole blood


Light Blue top tube (Buffered Na Citrate 3.2%)

Draw Volume:

2.7 mL blood in a 3 mL tube (Minimum: 1.8 mL blood in a 2 mL tube)

Processed Volume:

0.9 mL (Minimum: 0.5 mL) plasma


A clean venipuncture is essential.

Do Not use the first 2 mL of blood collected.

Patient’s with hematocrit levels >55% must have a special tube made to adjust for the hematocrit; contact laboratory for special tube.

Mix by gentle inversion.


Special Processing:

Lab Staff: Do Not process if arriving within 24 hours. Send as whole blood. Ship at room temperature.

If greater than 24 hours is required for transport, centrifuge specimen, aliquot/transfer plasma into a screw-top plastic vial and freeze. Send frozen specimen on dry ice.

Patient Preparation:


Sample Rejection:

Improper tube; clotted samples; underfilled tubes; overfilled tubes; mislabeled or unlabeled specimens


Reference Range:

200 – 420 mg/dL

Critical Values:

<100 mg/dL


This method is sensitive to functional fibrinogen and insensitive to nonclottable fibrinogen and fibrin derivatives.


Electromagnetic clot detection


Fairview University Medical Center Web Page


5/21/2004: Reference range updated to 200 – 420 mg/dL for all ages. Previously listed as 170 – 370 mg/dL for patients greater than or equal to one year of age.
5/24/2010: Tubing patient specimens is no longer prohibited.
8/19/15: Critical range update, previously listed as <150 mg/dL.