Tried, true and new—mastering treatments

Here are a few treatment options we’re especially proud of:

  • Helping patients manage PHACES syndrome, a rare condition marked by hemangiomas along with birth defects of the heart, brain, skin, eyes or arteries. We’ve also been involved with the international PHACES registry.
  • Managing lymphangiomatosis, a rare disease of the lymphatic system, using interferon treatment and other new treatments such as the drug sirolimus.
  • Treating complicated vascular malformations with embolization and sclerotherapy procedures using new drugs such as Bleomycin.
  • Using new types of laser therapy to treat vascular anomalies.


At Children’s, we focus on research and innovations that make a difference at the bedside. From improving day-to-day quality of life for children and teens, to developing new pain management approaches and adopting cutting-edge technologies, our research is completely kid and family-focused.

Children’s is engaged in many types of research, including investigator-initiated studies (led by a Children’s clinician), as well as externally sponsored multicenter trials, observational studies and registries.

Research studies are ongoing in all areas of the hospital and clinics, but read more about vascular anomalies research below:

  • James Sidman, MD, surgical director of the vascular anomalies program, was part of a team whose study, “Assessment of Pulsed-Dye Laser Therapy for Pediatric Cutaneous Vascular Anomalies,” was published in the Sept. 5, 2013 National Center for Biotechnology Information.
  • Gits CC, Nelson SC, Feltis BA, Alexander JQ. Multimodal therapy in the treatment of a venolymphatic malformation of the axilla and chest wall in an infant.  J Vasc Surg Venous Lymphat Disord. 2014 Oct;2(4):451-4. doi: 10.1016/j.jvsv.2013.11.006. Epub 2014 Jan 16
  • Alexander JQ and Nelson SC. 13 year old boy with disabling right leg venous claudication and iliac vein hypoplasia. Controversies in Vascular Anomalies, NY Academy of Sciences, May 5-6, 2017. New York, NY.
  • Chu B, Han BK, McAllister NR, Nelson SC, Galliani C, Overman D. Intramuscular Capillary Hemangioma Isolated to the Right Ventricle in an Asymptomatic Young Child: A Case Report. American Society of Echocardiography, June 22-26, 2018. Nashville, TN.



At Children’s Minnesota, we know how important reliable information about conditions and illnesses is.