Children’s Minnesota has created a number of clinical practice guidelines for health professionals that highlight an evidence-based approach to the management of certain conditions in order to reduce unwarranted variation in care.
Guidelines are designed to apply to the bulk of patients with a given condition and should be adapted to individual patients based upon clinical judgment and individual situations. To assist providers with real-time decision making, most of the clinical guidelines at Children’s Minnesota consist of visual treatment algorithms/pathways, evidence-based ordersets, bibliographies and any applicable rules/alerts embedded within the electronic health record. In addition to clinical guidelines in pdf format listed below, more than 25 of the Children’s Minnesota clinical guidelines are available in interactive digital format through an avoMD guidelines application, which is accessible for providers on internal platforms and mobile devices.
Adnexal/Ovarian Torsion
Adnexal/Ovarian TorsionAllergy/Anaphylaxis
Anaphylaxis Guideline Beta-Lactam Allergy GuidelineAnemia
Adolescent with Anemia and Historic or Current Heavy Menstrual Bleeding Iron Deficiency Anemia in Patients ≤ 5 Years OldAppendicitis
Appendicitis: ED and Inpatient/Surgical GuidelineAsthma
Asthma Exacerbation ED/Inpatient Guideline Asthma Outpatient GuidelineBrief Resolved Unexplained Event (BRUE)
Brief Resolved Unexplained Event (BRUE) GuidelineBronchiolitis
Bronchiolitis GuidelineButton Battery Ingestion
Button Battery GuidelineCannabinoid Hyperemesis Syndrome
Cannabinoid Hyperemesis Syndrome GuidelineCardiac Rehabilitation
Cardiac Rehabilitation GuidelineCervical Spine Clearance
Cervical Spine Clearance GuidelineCongenital CMV Guideline
Congenital CMV GuidelineClostridioides Difficile Infection (CDI)
COVID-19 (Coronavirus) Interim Guidelines
Coronavirus Interim Guidelines have not been through the formal guideline governance council review process but have been approved for interim use by clinical leaders. They should be viewed as interim guidelines and will be updated frequently as the situation evolves. Health care providers should also refer to external sources such as CDC.gov and the Minnesota Department of Health for additional resources for this dynamic situation. Diagnostic testing strategy Medical Management for patients with confirmed COVID-19 Suspected MIS-C management recommendations VTE Prophylaxis in COVID-19 patients – see below under VTE Risk Stratification in Hospitalized Patients (includes Patients with COVID) Paxlovid Prescribing ProcessCroup
Croup Guideline: Age 3 Months-8 YearsFever ≥ 38.0°C (100.4°F) Without Obvious Source (Infant 1-60 Days)
Febrile Infant ED/Inpatient GuidelineFever and Neutropenia
Fever and Neutropenia Treatment GuidelineHigh Flow Nasal Cannula
High Flow Nasal Cannula Guideline