Children’s Minnesota has created a number of clinical practice guidelines for health professionals that highlight an evidence-based approach to the management of certain conditions in order to reduce unwarranted variation in care.
Guidelines are designed to apply to the bulk of patients with a given condition and should be adapted to individual patients based upon clinical judgment and individual situations. To assist providers with real-time decision making, most of the clinical guidelines at Children’s Minnesota consist of visual treatment algorithms/pathways, evidence-based ordersets, bibliographies and any applicable rules/alerts embedded within the electronic health record. In addition to clinical guidelines in pdf format listed below, more than 25 of the Children’s Minnesota clinical guidelines are available in interactive digital format through an avoMD guidelines application, which is accessible for providers on internal platforms and mobile devices.
Clinical guidelines
Acetaminophen Poisoning
Acetaminophen Poisoning GuidelineAdnexal/Ovarian Torsion
Adnexal/Ovarian TorsionAllergy/Anaphylaxis
Anaphylaxis Guideline Beta-Lactam Allergy GuidelineAnemia
Anemia in Patients with Heavy Menstruation Iron Deficiency Anemia in Patients ≤ 5 Years OldAppendicitis
Appendicitis: ED and Inpatient/Surgical GuidelineAsthma
Asthma Exacerbation ED/Inpatient Guideline Asthma Outpatient GuidelineBrief Resolved Unexplained Event (BRUE)
Brief Resolved Unexplained Event (BRUE) GuidelineBronchiolitis
Bronchiolitis GuidelineButton Battery Ingestion
Button Battery GuidelineCannabinoid Hyperemesis Syndrome
Cannabinoid Hyperemesis Syndrome Guideline
Cardiac Rehabilitation
Cardiac Rehabilitation Guideline
Cervical Spine Clearance
Cervical Spine Clearance Guideline
Congenital CMV Guideline
Clostridioides Difficile Infection (CDI)
C. Difficile Testing Guideline
C. Difficile Treatment Algorithm
COVID-19 (Coronavirus) Interim Guidelines
Coronavirus Interim Guidelines have not been through the formal guideline governance council review process but have been approved for interim use by clinical leaders. They should be viewed as interim guidelines and will be updated frequently as the situation evolves. Health care providers should also refer to external sources such as CDC.gov and the Minnesota Department of Health for additional resources for this dynamic situation.
Diagnostic testing strategy
Medical Management for patients with confirmed COVID-19
Suspected MIS-C management recommendations
VTE Prophylaxis in COVID-19 patients – see below under VTE Risk Stratification in Hospitalized Patients (includes Patients with COVID)
Paxlovid Prescribing Process
Croup
Diabetes
ED and Med-Surg Diabetes GuidelineFever ≥ 38.0°C (100.4°F) Without Obvious Source (Infant 1-60 Days)
Febrile Infant ED/Inpatient GuidelineFever and Neutropenia
Fever and Neutropenia Treatment GuidelineGastroenteritis
Acute Gastroenteritis Inpatient Guideline
Oral Rehydration Therapy – Less than 10kg Hmong, Somali, Spanish
Oral Rehydration Therapy – More than 10kg Hmong, Somali, Spanish
Gastroesophageal Reflux (GER/GERD)
CHN Guidelines for Outpatient Medical Management of Children with Gastroesophageal Reflux
High Flow Nasal Cannula
High Flow Nasal Cannula GuidelineHypothermia, Accidental – Trauma
Accidental Primary Hypothermia (HT) GuidelineIntussusception
Intussusception ED Clinical GuidelineJaundice
Hyperbilirubinemia GuidelineKawasaki Disease
Kawasaki Disease GuidelineSuspected Kidney Stone
Suspected Kidney StoneMASLD Primary Care
Metabolic Dysfunction-Associated Steatotic Liver Disease GuidelineMeasles
Measles Management GuidelineMeningitis
Meningitis GuidelineMenstrual Bleeding
Anemia in Patients with Heavy MenstruationMusculoskeletal (MSK)
Musculoskeletal (MSK) Infection GuidelineNasogastric (NG) Tube
Nasogastric (NG) Tube Discharge Planning Guideline
Neurogenic Bladder and Bowel
Neurogenic Bladder Guidelines
Neurogenic Bowel Guidelines
Nothing by Mouth (NPO)
Open Fracture – Trauma
Antibiotic Prophylaxis in Patients with Open FracturesOpioid Withdrawal Guideline
Opioid Withdrawal GuidelineOtitis Media
Otitis Media GuidelinePenicillin Allergy Delabeling
Penicillin Allergy Delabeling Guideline
Pharmacy
Key potentially inappropriate drugs in pediatrics: The Kids List
Pneumonia
Community Acquired Pneumonia Inpatient Guideline
Pneumonia Complicated by Empyema Inpatient Guideline
Post-op Thyroidectomy Management
Post-op Thyroidectomy Management Guideline
Pneumothorax
Primary Spontaneous Pneumothorax (PSP) Guideline
Preseptal/Orbital Cellulitis
Rehabilitation
New Tracheostomy Recovery/Rehabilitation in PICU GuidelineSeizure and Status Epilepticus
Febrile Seizure Guideline Seizure and Status Epilepticus GuidelineSickle Cell
Sickle Cell Vaso-Occlusive Pain Episode Management GuidelineSuspected Shunt Malfunction or Infection
Suspected Shunt Malfunction or Infection ED GuidelineSkin and Soft Tissue Infections (SSTIs)
Skin and Soft Tissue Infections GuidelineSolid Organ Injury – Trauma
Solid Organ Injury Management GuidelineSpeaking and Swallowing Valve (Passy-Muir)
Speaking and Swallowing Valve (Passy-Muir) Guideline: Inline Valve TrialStroke
Cerebral Venous Sinus Thrombosis CVST Guideline ED Suspected Stroke Guideline Inpatient Suspected Stroke GuidelineSurgical Antibiotic Prophylaxis
Comprehensive Surgical Antibiotic Prophylaxis GuidelineTesticular Torsion
Evaluation of Potential Testicular Torsion Guideline
Tonsillectomy
Post-tonsillectomy Hemorrhage
Tonsillectomy +/- Adenoidectomy
