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Children’s Minnesota has created a number of clinical practice guidelines for health professionals that highlight an evidence-based approach to the management of certain conditions in order to reduce unwarranted variation in care.
Guidelines are designed to apply to the bulk of patients with a given condition and should be adapted to individual patients based upon clinical judgment and individual situations. To assist providers with real-time decision making, most of the clinical guidelines at Children’s Minnesota consist of visual treatment algorithms/pathways, evidence-based ordersets, bibliographies and any applicable rules/alerts embedded within the electronic health record. In addition to clinical guidelines in pdf format listed below, more than 25 of the Children’s Minnesota clinical guidelines are available in interactive digital format through an avoMD guidelines application, which is accessible for providers on internal platforms and mobile devices.
Brief Resolved Unexplained Event (BRUE)
Button Battery Ingestion
Cannabinoid Hyperemesis Syndrome
Cervical Spine Clearance
Congenital CMV Guideline
Clostridioides Difficile Infection (CDI)
COVID-19 (Coronavirus) Interim Guidelines
Coronavirus Interim Guidelines have not been through the formal guideline governance council review process but have been approved for interim use by clinical leaders. They should be viewed as interim guidelines and will be updated frequently as the situation evolves. Health care providers should also refer to external sources such as CDC.gov and the Minnesota Department of Health for additional resources for this dynamic situation.
Suspected MIS-C management recommendations
VTE Prophylaxis in COVID-19 patients – see below under VTE Risk Stratification in Hospitalized Patients (includes Patients with COVID)
Fever ≥ 38.0°C (100.4°F) Without Obvious Source (Infant 1-60 Days)
Fever and Neutropenia
High Flow Nasal Cannula
Hypothermia, Accidental – Trauma
Suspected Kidney Stone
MASLD Primary Care
Neurogenic Bladder and Bowel
Nothing by Mouth (NPO)
Open Fracture – Trauma
Opioid Withdrawal Guideline
Penicillin Allergy Delabeling
Post-op Thyroidectomy Management
Seizure and Status Epilepticus
Suspected Shunt Malfunction or Infection
Skin and Soft Tissue Infections (SSTIs)
Solid Organ Injury – Trauma
Speaking and Swallowing Valve (Passy-Muir)
Surgical Antibiotic Prophylaxis
Urinary Tract Infections (UTI)
Venous Thromboembolism (VTE)
Guidelines are updated periodically in keeping with emerging evidence. Each guideline contains an important disclaimer and users must proceed at their own risk accordingly: This guideline is designed for general use with most patients; each clinician should use his or her own independent judgment to meet the needs of each individual patient. This guideline is not a substitute for professional medical advice, diagnosis or treatment.
For more information, email [email protected].