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Win Rho

How does this medicine work?

Win Rho can be given only to Rh-positive persons who have idiopathic thrombocyopenia purpura (ITP), and who have not had their spleen removed. ITP means platelets (cells that help with blood clotting) are destroyed in the body. Win Rho may temporarily increase platelet counts in these patients.

Win Rho is a human plasma product that has been specially treated to remove viruses.

Win Rho usually begins to work in 1 to 2 days, with a peak effect in 7 to 14 days. It lasts an average of 1 to 3 weeks and has been effective for up to 5 months. Repeat doses may be needed.

How is it given?

Win Rho is given into a vein (IV) in the hospital or clinic.

What are the side effects?

Win Rho has fewer side effects than other ITP treatments, steroids or gammaglobulin.


  •  reduced hemoglobin


  • dark urine
  • severe headaches
  • fever, chills


  • fever or chills
  • rash or hives
  • kidney failure
  • wheezing

When should I call the doctor?

  • fever or chills
  • persistent headache not helped by acetaminophen (such as Tylenol®)
  • dark urine
  • back pain
  • pale or blue color in the lips or skin
  • signs of an allergic reaction
    • sudden rash or hives
    • itching
    • wheezing
    • trouble breathing - call 911

What else do I need to know?

Your child's hemoglobin will be monitored during treatment with Win Rho.

Give acetaminophen (such as Tylenol®) for headaches or fever. Do not give aspirin or ibuprofen (Advil® or other brands).

You and your child should know the names of all the medicines he or she is taking. Share this information with anyone involved in your child's care.

Check with the doctor, nurse practitioner, or pharmacist before giving any other prescription or non-prescription medicines, herbs, or vitamins.


This sheet is not specific to your child but provides general information. If you have any questions, please call the hematology/oncology clinic or pharmacy.

Children's Hospitals and Clinics of Minnesota
Patient/Family Education
2525 Chicago Avenue South
Minneapolis, MN 55404
Last reviewed 8/2015 ©Copyright

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This page is not specific to your child, but provides general information on the topic above. If you have any questions, please call your clinic. For more reading material about this and other health topics, please call or visit Children's Minnesota Family Resource Center library, or visit

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