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Epidermolysis bullosa: Dressing care

Dressings for epidermolysis bullosa can be used for protection of skin or for wound healing. 

The layer next to the skin should be non-stick. The secondary layer gives padding and protection, and the third layer keeps the dressing in place.

  1. Bathe the skin using water, salt, bleach or vinegar baths.
  2. Keep the wounds moist with white petrolatum (such as Vaseline or Aquaphor).
  3. Apply topical antibiotic if ordered by your provider.
  4. Place a primary contact layer (such as Mepitel) on the wound as needed.
  5. Place a secondary dressing for wound protection. You and your provider may decide on a number of dressings, which may include foam dressings.
  6. If no contact layer is needed, the secondary dressing will go directly on the skin.
  7. Wrap the area with Kerlix gauze if needed.
  8. To secure the dressing, paper tape (such as Tubifast) may be used.

For fingers:

  1. Follow steps 1-4 above.
  2. You doctor may prescribe conform-rolled gauze (such as Flexicon) to secure the contact layer in place and promote finger movement. Work with your occupational therapist to create a dressing that is appropriate for you and your child.

What else do I need to know about wound care?

  • Warmer temperatures may increase blister formation as they make the skin more fragile.
  • If your child has mouth sores, be sure to discuss feeding techniques with your doctor.
  • Dress your child in soft clothing. Shirts and onesies can be turned inside out to prevent the seams from harming the skin.  Elastic cuffs can be removed from clothing and diapers to prevent harm to the skin.
  • Sheepskin and foam overlays on the bed can be placed under sheeting or in chairs to prevent skin trauma.
  • Your child will likely require more calories and fluids due to his or her skin disease.
  • IVs and lines should be secured with transparent, non-stick dressings that protect the skin.


This information is not specific to your child. If you have questions, contact your clinic or health care provider.

Reviewed by Skin Integrity Team 9/2016

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This page is not specific to your child, but provides general information on the topic above. If you have any questions, please call your clinic. For more reading material about this and other health topics, please call or visit Children's Minnesota Family Resource Center library, or visit

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