24/7 referral, consult, admission and neonatal transport assistance.


The immunology program at Children’s Minnesota evaluates and treats kids with a wide spectrum of immune challenges, ranging from severe inherited immunodeficiencies in young infants and children to secondary immune problems in children who require various immunosuppressant medications.

Conditions treated

There are nearly 400 genetically unique inherited immunodeficiencies – these are rare and distinct conditions.

Some examples of conditions we see frequently treat

  • Severe combined immune deficiency (SCID) or “boy in the bubble” disease
  • Hyper IgM syndrome
  • Chronic granulomatous disease (CGD)
  • HyperIgE syndrome
  • DiGeorge syndrome
  • X-linked agammaglobulinemia (XLA)
  • Transient low antibody levels (hypogammaglobulinemia) of infancy
  • IgA deficiency
  • Common variable immune deficiency (CVID)

We also assess and support children whose immune systems are low secondary to medications they require for autoimmune or other conditions. One example would be kids who’ve needed rituximab which can result in low antibody levels.

Services offered

  • Diagnosis and treatment of immune defects ranging from transient hypogammagloblobulinemia of infancy to severe combined immune deficiency (SCID)
  • Close collaboration with Children’s Genetics for diagnosis of inherited immune problems to inform personalized medicine recommendations
  • Management of intravenous and subcutaneous immunoglobulin infusions
  • Ongoing immunologic cares for kids with 22q11.2 deletion syndrome, also known as DiGeorge syndrome including those who attend the monthly multidisciplinary Children’s Velocardiofacial Clinic
  • Clinical support of community providers with immunology questions

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Related Specialty

  • Genetics/Genomics
  • Hematology/Oncology

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